Manual A step-by-step guide to NextDose. See also NextDose Web

Logging in

1. Go to www.nextdose.org
2. Enter your institutional email address and password
3. Click login

NextDose workspace

Create a new patient

1. Click New patient at the top of the patient list
2. Enter a unique ID (NHI in New Zealand)
3. Choose a sex
4. Enter date of birth or age
5. Optionally enter the patient's name(s) and other information
6. Click Save changes

Add a medicine to a patient

1. Click Add a new medicine at the top right of the screen
2. Click on the medicine you want to add
3. The Doses & observations pane will be displayed
4. A form is displayed on the right, where you can enter information about doses and observations. Weight is selected by default.
5. Enter the patients weight and the date and time of the measurement
6. Click Save changes
7. Continue to add more doses and observations

Adding doses

1. Click Add dose at the bottom middle of the screen
2. Enter the date and time of the dose (start time if the dose is an infusion)
3. Choose the route and unit of the dose from the dropdown menu
4. Enter the dose
5. If the dose is an infusion, you can enter the duration of the infusion (minutes or hours) or the date and time that the infusion ended. If left blank, the infusion is assumed to be a bolus (less than 1 minute).
6. If the same dose is repeated multiple times at a constant interval, check the Repeat checkbox. You cannot use a specific infusion end date/time if this option is selected.
7. If repeating doses, enter the dose interval and the number of doses. Click At steady state if the patient is likely to be at steady state at the time date/time specified for the dose record e.g. the patient is on long-term tacrolimus
8. Click Save changes

Adding observations

Observations include concentration and other lab measurements in addition to clinical observations such as weight and height

1. Click Add observation at the bottom middle of the screen
2. Choose the observation type from the dropdown menu
3. Enter the date and time of the observation (collection time for lab measurements)
4. Optionally enter the sample arrival time for lab measurements
5. Enter the value of the observation. If below the limit of quantitation, click BLQ.
6. Optionally enter a lab number for auditing purposes
7. Click Save changes

Navigating patients and records

• Patients in the groups you belong to are listed on the left
• You can search/filter this list by typing into the search box at the top of the list
• Click on a patient to make them active. This will display their details in the main section. A list of records will appear below their name in the patient list.
• Click on records (date/times) to navigate between them.

Navigating within records

• Each record is divided into tabs, displayed near the top of the screen
• Patient details shows the same information for a patient, irrespective of which record is selected.
• Doses & observations shows medicine-specific input for the record and allows editing.
• Results shows the report generated based on the input for the record. If the calculation has not yet been run, some options are displayed along with a button to start the calculation.
• Print include some output options and a button to generate a printer-friendly report of input data and calculation results
• Delete allows deletion of a record

Results

1. Click the results tab. If a calculation has been run, the report will be displayed. Otherwise calculation options will appear.
2. Choose one or more Dependant variables. Check only concentration if unsure.
3. The Target and Dose interval can be changed from the defaults displayed
4. The Calculation comment can be useful for organising multiple reports by briefly describing differences between them
5. Click Calculate and wait up to 30 seconds for the report to be generated
6. A report, or error message will be displayed

Printing

1. Click the print tab. A calculation for the record must have been run in order to print.
2. Optionally enter the name of the Consultant in charge to be attached to the report
3. Optionally add Additional comments to appear on the printed report
4. Click Print. You will be directed to a printer-friendly report.

Account menu

The account menu is labelled with your name and is located in the top right corner of the screen. It provides:

• account management
• group administration if you are an administrator of any groups
• sign out