NextDose Bayesian forecasting dose calculator

A free web-based dose calculator using concentration guided dosing with Bayesian forecasting and the target concentration intervention approach
for busulfan, methotrexate, tacrolimus, warfarin, linezolid, voriconazole, gentamicin, tobramycin, amikacin, vancomycin, caffeine, mycophenolate, hydroxychloroquine, dabigatran, posaconazole, gancyclovir/valgancyclovir, clozapine and enoxaparin.

22-Oct-2026: NextDose Outage
-NextDose Access: A serious bug in the PHP system used with NextDose required immediate attention. The PHP system is used by the majority of web servers in the world. NextDose was taken off line at 2:55 am NZDT to install a PHP patch and restored at 4:48 pm NZDT. Thanks to Greg Trounson (University of Otago IT) for his quick work in protecting NextDose data. Unfortunately, the patch may have changed the way NextDose produces some results e.g. mycophenolate, while other results are unchanged e.g. busulfan, vancomycin, gentamicin, amikacin, tacrolimus, linezolid, warfarin. We are investigating this problem and hope to find a solution as soon as possible. Users are urged to check results after the patch with those obtained before the patch using the same Patient Details and Doses and Observations in both cases. If the results are the same then you may then makes changes toPatient Details and Doses and Observations and use calculate new Results. If you are unable to confirm results before and after the patch then exercise increased caution about the plausibility of the results.

26-Jul-2026: NextDose Version Change to 2.6.02
-Bug fix: A problem for some web browsers to show Time in the NextDose Doses and Observations tab has been fixed.

- Feedback, and the reporting of any issues encountered, is always appreciated.

NextDose Updates

Anyone may sign up for single user access. Access to share patient data within a secure group can be applied for here.

Note that patient data stored on dev.nextdose.org is not transferable to www.nextdose.org. The dev.nextdose.org web is under active development and may change without notice as features are tested and bugs fixed.